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THE IMMUNE SYSTEM

 

       Immune system of our body
is dependent upon the defense cells we produce continuously from
the red bone marrow and the other organs like liver and spleen.
The primary defense shield we are having is the best- which is
the external epithelial covering of our internal delicate
tissues. The epithelial tissue of skin have on it’s outer
surface keratin cells which are basically dead cells which are
filled with keratin- an inert material which provides a fine
barrier between the outer world full of microbiota (which are
very alive, of course!) and our inner sensitive and unprotected
connective tissues which contain all the blood vessels and
nerves.      

 The second defensive
mechanism active can be said to be the Leucocytes, which are
called PMN’s (Poly Morpho Nuclear Leucocytes) and these have so
many defensive pathways inside them like oxidative enzymes,
lysozymes, factors which would attract other leucocytes from the
central processing unit and triggering mechanisms to alert the
higher immunal mechanisms; if they cannot contain the invading
colonies of microorganisms. The fact is that we are essentially
in a perpetual war situation every day every moment, but we are
not conscious about it. 

       The last line of defense
before the infection reaches deeper layers would be the
activation of humoral and cellular arms of the Immune System,
with the Macrophages, Giant cells, and Lymphocytes migrating to
the local site where PMN’s are just loosing the war, by hordes
of alien organisms invading into the connective tissue layers.
The Lymphocytes are so powerful destructive agents that the
infection would be contained with a very high probability and as
most of these warrior cells have tendency to self destruct along
with the ingested organisms ( if all other techniques fail), the
lysing enzymes along with remnants of the dead bacteria after
sometime start dissolving some parts of the host cells also,
leading to local necrosis and pain. Pain is an important event
in notifying the host about the war which is going in his own
body, and so the pain producing agents like Prostaglandin
byproducts are released to alarm host about the fact that
external help may be needed in an extreme situation.

       Our immune system is so
efficient that normally an attack even of the highest degree
would be ineffective provided; the host is able to supply the
nutrients to the synthesizing centers for continued production
and replenishment of defense cells, the immune system has a
database where all these attacking organisms are categorized and
their weaknesses and potential weapons (like Osteoclast
Activating Factor, Various Enzymes, Macrophage Migration
Inhibitory Factor, and various degrading and destructive
enzymes) are recognized and antibodies can be readily prepared,
the attacking colonies are not of extremely dangerous variety
like particular viruses, and most importantly the host has a
mental status which is not of a depressed nature ( which leads
to adrenal and other lower endocrine gland secretion which would
affect the production of defense cells and would affect the
outcome of battle).

 

 

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